| ncRNA name | hsa-miR-27b |
| ncRNA Category | miRNA |
| Disease name | choroidal neovascularization (CNV) |
| Species | Homo sapiens |
| Tissues/Cell_line | human umbilical vein endothelial cells (HUVECs) |
| Methods | transfection, qRT-PCR, Northern blot, Western blot, luciferase reporter assay |
| Expression pattern | up-regulated |
| Functional description | miR-23 and miR-27 enhance angiogenesis by promoting angiogenic signaling through targeting Sprouty2 and Sema6A proteins, which exert antiangiogenic activity. |
| PubMed ID | 21536891 |
| Year | 2011 |
| Title | Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23~27~24 clusters. |
| Drug-related ncRNA | NO |
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